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Invitrogen™ Human CD150 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP1237
Additional Details : Weight : 0.01000kg
Description
SLAMF1 Synthetic Peptide, PEP-1237, from Invitrogen.
CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP). This peptide corresponds to 15 amino acids near the amino terminus of human SLAMF1.PEP-1237 can be used as a blocking peptide with polyclonal antibody PA5-21123.Specifications
6504 | |
purified | |
Human CD150 | |
-20°C | |
Liquid | |
Blocking Assay, Control | |
No | |
Peptide | |
RUO - research use only |
Human | |
Q13291 | |
200 μg/mL | |
Synthetic Peptide | |
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
SLAMF1 | |
0.02% sodium azide | |
50 μg | |
PBS |