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  8. Sivelestat sodium tetrahydrate, MedChemExpress

Sivelestat sodium tetrahydrate, MedChemExpress

Product Code. 16463367
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Product Code. 16463367

Brand: Medchem Express HY17443B

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Description

MedChemExpress Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Specifications

Chemical Name or Material Sivelestat sodium tetrahydrate
CAS 201677-61-4
Color White
Purity Grade Notes Research
Molecular Formula C20H29N2NaO11S
Quantity 50 mg
Synonym EI546 sodium tetrahydrateLY544349 sodium tetrahydrateONO5046 sodium tetrahydrate
Solubility Information DMSO : 250 mg/mL (473.03 mM; Need ultrasonic)
SMILES CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O[Na])=O)=O)=O)C=C1)=O.O.O.O.O
Molecular Weight (g/mol) 528.51
Formula Weight 528.51
Percent Purity 99.06%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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