missing translation for 'onlineSavingsMsg'
Learn More

SETD7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24840-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16893335

  • 3468.15 NOK / 150µL
Estimated Shipment: 15-12-2022
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Histone methyltransferase that specifically monomethylates ′Lys-4′ of histone H3. H3 ′Lys-4′ methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates ′Lys-189′ of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates ′Lys-372′ of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated ′Lys-372′ of p53/TP53 in vitro.
Specifications

Specifications

SETD7
Polyclonal
Unconjugated
SETD7
H3 K4 HMTase SETD7, KIAA1717, KMT7, Lysine N methyltransferase 7, SET7, SET7/9, SET9, SETD7
Rabbit
Antigen Affinity Chromatography
RUO
689954, 73251, 80854
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8VHL1, Q8WTS6
Setd7
SETD7 Fusion Protein Ag18219
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Videos
SDS
Documents
Certificates
Special Offers

Special Offers