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Selumetinib, MedChemExpress

Product Code. 16491916
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Product Code. 16491916 Supplier Medchem Express Supplier No. HY50706

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Description

MedChemExpress Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Specifications

Chemical Name or Material Selumetinib
CAS 606143-52-6
Color White
Purity Grade Notes Research
Molecular Formula C17H15BrClFN4O3
Quantity 500 mg
Synonym AZD6244 ARRY-142886
Solubility Information DMSO : 10 mg/mL (21.85 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O=C(C1=C(C(F)=C2N=CN(C2=C1)C)NC3=CC=C(C=C3Cl)Br)NOCCO
Molecular Weight (g/mol) 457.68
Formula Weight 457.68
Percent Purity 98.01%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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