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Description
SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
Specifications
Specifications
| Antigen | SEC14L1 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | SEC14L1 |
| Gene Accession No. | Q92503 |
| Gene Alias | PRELID4A, SEC14 like 1 (S. cerevisiae), SEC14 like protein 1, SEC14L, SEC14L1 |
| Gene Symbols | SEC14L1 |
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Product Title
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