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SCH772984, MedChemExpress

Product Code. p-200098504
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Product Code. 16478108

Brand: Medchem Express HY50846

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Description

MedChemExpress SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-naïve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations.

SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-naïve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations.

Specifications

Chemical Name or Material SCH772984
CAS 942183-80-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C33H33N9O2
Quantity 10 mg
Solubility Information DMSO : 48 mg/mL (81.68 mM; Need ultrasonic)
SMILES O=C([C@H](CC1)CN1CC(N(CC2)CCN2C(C=C3)=CC=C3C4=NC=CC=N4)=O)NC5=CC6=C(C=C5)NN=C6C7=CC=NC=C7
Molecular Weight (g/mol) 587.67
Formula Weight 587.67
Percent Purity 98.69%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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