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SC75741, MedChemExpress

Product Code. 16470357
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Product Code. 16470357

Brand: Medchem Express HY10496

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Description

MedChemExpress SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.

SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins.

Specifications

Chemical Name or Material SC75741
CAS 913822-46-5
Color Brown
Purity Grade Notes Research
Molecular Formula C29H23N7O2S2
Quantity 50 mg
Solubility Information DMSO : 83.33 mg/mL (147.31 mM; Need ultrasonic)
SMILES O=C(NC1=NC(C=CC(C(C2=CC=CC=C2)=O)=C3)=C3N1)C4=CSC(C(CC5)CCN5C6=NC=NC7=C6SC=C7)=N4
Molecular Weight (g/mol) 565.67
Formula Weight 565.67
Percent Purity 98.02%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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