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Tocris Bioscience™ SB 706504
GREENER_CHOICE

p38 MAPK inhibitor

Brand:  Tocris Bioscience™ 5040/50

Encompass

Product Code. 15766396

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Description

Description

SB 706504 is a p38 MAPK inhibitor. Inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs). Also inhibits LPS-induced protein expression of IL-6, IL-10, TNFα and γ-inducible protein 10 in COPD MDMs. Effects on suppression of LPS-induced gene and protein expression are enhanced in combination with dexamethasone (Cat. No. 1126).
Specifications

Specifications

N-Cyano-N′-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine
911110-38-8
50 mg
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