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ACROBiosystems SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (MALS verified)

Brand:  ACROBiosystems SPD-C52Hr-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 17206530

  • 5494.32 NOK / 100µg
Estimated Shipment: 05-06-2024
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Description

Description

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

QHD43416.1 (K417T, E484K, N501Y)
100 μg
Arg 319 - Lys 537
Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD,COVID-19
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE.
26.5 kDa
SARS-CoV-2 S protein RBD (K417T, E484K, N501Y), His Tag (SPD-C52Hr) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (K417T, E484K, N501Y)). K417T/ E484K/ N501Y mutations were identified in the SARS-CoV-2 variant (known as variant P0.1) which emerged in Brazil.
-20°C
S protein RBD
SARS-CoV-2
PBS, pH7.4
HEK293
Viral Proteins
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