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S100A12 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16630-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16886304

  • 3468.15 NOK / 150µL
Estimated Shipment: 19-12-2022
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Description

Description

S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.
Specifications

Specifications

S100A12
Polyclonal
Unconjugated
S100A12
CAAF1, CAGC, Calgranulin C, CGRP, EN RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100A12
Rabbit
Antigen Affinity Chromatography
RUO
6283
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.37 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P80511
S100A12
S100A12 Fusion Protein Ag9961
150 μL
Primary
Human
Antibody
IgG
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