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S100A12 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16886304 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16886304 150 μL 150µL
16896304 20 μL 20µL
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Product Code. 16886304

Brand: Proteintech 166301AP150UL

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This item is not returnable. View return policy

Rabbit Polyclonal Antibody

S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.

Specifications

Antigen S100A12
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene S100A12
Gene Accession No. P80511
Gene Alias CAAF1, CAGC, Calgranulin C, CGRP, EN RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, Protein S100 A12, S100A12
Gene Symbols S100A12
Host Species Rabbit
Immunogen S100A12 Fusion Protein Ag9961
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6283
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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