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RPS10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14894-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893784

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S10 (RPS10) is a 165 amino acid component of the small ribosomal 40S subunit. While generally found in the cytoplasm, RPS10 can localize to the granular component (GC) region of the nucleolus. For this to occur, methylation by PRMT5 is required as well as an interaction with NPS1. Defects in RPS10 are the cause of Diamond-Blackfan anemia type 9 (DBA9). It is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of maligcy.
Specifications

Specifications

RPS10
Polyclonal
Unconjugated
RPS10
40S ribosomal protein S10, ribosomal protein S10, RPS10
Rabbit
Antigen Affinity Chromatography
RUO
6204, 67097, 81773
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P46783, P63325, P63326
RPS10
RPS10 Fusion Protein Ag6683
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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