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  8. RO8994, MedChemExpress

RO8994, MedChemExpress

Product Code. p-200102116
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Product Code. Quantity unitSize
16497216 100 mg 100mg
16489777 5 mg 5mg
16483267 50 mg 50mg
16427258 10 mg 10mg
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Product Code. 16497216

Brand: Medchem Express HY16999

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Description

MedChemExpress RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays).

RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays).

Specifications

Chemical Name or Material RO8994
CAS 1309684-94-3
Color White
Purity Grade Notes Research
Molecular Formula C31H31Cl2FN4O4
Quantity 100 mg
Solubility Information DMSO : ≥ 45 mg/mL (73.35 mM)
SMILES O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)NC5=CC=C(C(N)=O)C=C5OC
Molecular Weight (g/mol) 613.51
Formula Weight 613.51
Percent Purity 98.95%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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