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RN-1734, MedChemExpress
MedChemExpress RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.
853.40 NOK - 6779.81 NOK
Specifications
| Chemical Name or Material | RN-1734 |
|---|---|
| CAS | 946387-07-1 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C14H22Cl2N2O2S |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16483917
|
Medchem Express
HY-19975 |
50 mg |
4346.03 NOK
50mg |
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|
16450458
|
Medchem Express
HY-19975 |
5 mg |
853.40 NOK
5mg |
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|
16427776
|
Medchem Express
HY-19975 |
100 mg |
6779.81 NOK
100mg |
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|
16417998
|
Medchem Express
HY-19975 |
10 mg |
1390.73 NOK
10mg |
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Description
RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.Specifications
| RN-1734 | |
| White | |
| C14H22Cl2N2O2S | |
| O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O | |
| 353.31 | |
| Research | |
| Neuroscience-Neuromodulation |
| 946387-07-1 | |
| Research | |
| DMSO : 25 mg/mL (70.76 mM; ultrasonic and warming and heat to 60°C) | |
| 353.31 | |
| 98.99% | |
| Solid |
Safety and Handling
H302∣H315∣H319∣H335
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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