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Rifamycin SV Sodium Salt, MP Biomedicals™

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Quantity:
250 mg
Unit Size:
250mg
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Product Code. 11444772

Brand: MP Biomedicals 02191516.2

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This item is not returnable. View return policy

Description

Used to study potential genes that may be involved in the conversion of rifamycin SV into rifamycin B. Rifamycin SV Sodium Salt, MP Biomedicals is a broad-spectrum semisynthetic antimicrobial agent of the rifamycin group. It has limited oral absorption.

Rifamycin SV inhibits selective (E. coli, B. subtilis) bacterial DNA-dependent RNA polymerase by binding to the polymerase β-subunit, a mechanism similar to rifabutin. It acts as a selective cytochrome P450 3A4 inducer. It has limited oral absorption. It is active against Gram-positive bacteria and is moderately active against Gram-negative organisms.

  • Used to study potential genes, such as rif15 and rif16, which may be involved in the conversion of rifamycin SV into rifamycin B
  • Potential treatment for traveler’s diarrhea (TD), Clostridium difficile-associated disease (CDAD) and rheumatoid knee synovitis
  • It is used in electron spin resonance studies
TRUSTED_SUSTAINABILITY

Specifications

CAS 14897-39-3
Molecular Formula C37H47NNaO12
MDL Number MFCD09752825
Quantity 250 mg
Synonym rifamycin sodium salt, rifamycin sodium usan, rifamycin sv sodium salt, rifocina tn, otofa tn
Solubility Information Ethanol: soluble (50mg/mL)
InChI Key YVOFSHPIJOYKSH-DITFEXNXSA-N
SMILES [Na+].CO[C@H]1\C=C/O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C=C(O)C4=C3C2=O
IUPAC Name sodium (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1⁴,⁷.0⁵,²⁸]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
Molecular Weight (g/mol) 720.77
PubChem CID 124219641
Formula Weight 719.8
Physical Form Powder
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