missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Lipids and Lipid Derivatives
  5. Fatty acid conjugates
  6. Retinoic Acid, All Trans Isomer, MP Biomedicals™

Retinoic Acid, All Trans Isomer, MP Biomedicals™

Product Code. 11441771 Shop All MP Biomedicals Products
Click to view available options
Quantity:
50 mg
500 mg
Unit Size:
500mg
50mg
This item is not returnable. View return policy

Product Code. 11441771

Brand: MP Biomedicals 02190269.5

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Mediates the functions of vitamin A required for growth and development. Retinoic Acid, All Trans Isomer, MP Biomedicals has been used in various differentiation protocols, including B-cells, T cells and neurons, and is applied clinically to treat cancer

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule. It affects gene transcription and modulates a wide variety of biological processes, including cell proliferation and differentiation, including apoptosis.

  • Retinoic Acid mediated gene transcription depends on the rate of transport of Retinoic Acid to target cells and the timing of exposure of Retinoic Acid to RARs (Retinoic Acid Receptors) in the target tissues.
  • All-trans-Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).
  • The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells.
  • Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA.
  • Retinoic acid primes embryonic stem cells to become neurons.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 302-79-4
Molecular Formula C20H28O2
Molecular Weight (g/mol) 300.44
MDL Number MFCD00001551
InChI Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
Synonym retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
PubChem CID 444795
ChEBI CHEBI:15367
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

Specifications

Melting Point 173°C to 183°C
Quantity 500 mg
Solubility Information Soluble in methanol, chloroform (40mg/mL) or acetone (30mg/mL), slightly soluble in ethanol.
IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Formula Weight 300.4
Physical Form Powder
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.