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Invitrogen™ Human RET [V804E], GST Tag Recombinant Protein
This RET V804E Recombinant Human Protein (858-1114) was expressed in insect cells.
Brand: Invitrogen™ A33507
Additional Details : Weight : 0.10000kg
Description
- This RET V804E recombinant human protein (858–1114) was expressed in insect cells
- RET receptor tyrosine kinase or ret proto-oncogene is a member of the cadherin superfamily which are cell-surface receptors that transduce signals for cell growth and differentiation
- RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement
- Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia (type IIA), multiple endocrine neoplasia (type IIB), Hirschsprung disease, and medullary thyroid carcinoma
- RET signaling pathway plays a key role in the molecular mechanisms that orchestrate intestine organogenesis by regulating the development of both the nervous and lymphoid system in the gut
- RET V804E recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
NP_065681.1 | |
80.5 kDa | |
RET Kinase Family | |
Human | |
GST Tag | |
Dry Ice | |
Recombinant, Active, Cytoplasmic, Mutant |
Kinase Assay | |
10 μg | |
aa 858 - 1114 | |
Recombinant | |
Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol | |
Insect | |
Liquid |