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Invitrogen™ RET V804E Recombinant Human Protein

This RET V804E Recombinant Human Protein (858-1114) was expressed in insect cells.

Brand:  Invitrogen™ A33507

Additional Details : Weight : 0.10000kg

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Product Code. 15940413

  • 4725.00 NOK / 10µg
Estimated Shipment: 20-12-2022
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Description

Description

  • This RET V804E recombinant human protein (858–1114) was expressed in insect cells
  • RET receptor tyrosine kinase or ret proto-oncogene is a member of the cadherin superfamily which are cell-surface receptors that transduce signals for cell growth and differentiation
  • RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement
  • Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia (type IIA), multiple endocrine neoplasia (type IIB), Hirschsprung disease, and medullary thyroid carcinoma
  • RET signaling pathway plays a key role in the molecular mechanisms that orchestrate intestine organogenesis by regulating the development of both the nervous and lymphoid system in the gut
  • RET V804E recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z’-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_065681.1
10 µg
aa 858 - 1114
GST Tag
Dry Ice
Recombinant, Active, Cytoplasmic, Mutant
Kinase Assay
80.5 kDa
RET Kinase Family
Yes
Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol
Insect
Liquid
Human
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