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![Invitrogen™ Human RET [V804E], GST Tag Recombinant Protein Quantity: 1 mg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human RET [V804E], GST Tag Recombinant Protein
This RET V804E Recombinant Human Protein (858-1114) was expressed in insect cells.
Brand: Invitrogen™ A33730
Additional Details : Weight : 0.00900kg
Description
RET receptor tyrosine kinase or ret proto-oncogene is a member of the cadherin superfamily which are cell-surface receptors that transduce signals for cell growth and differentiation. RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. RET signaling pathway, by regulating the development of both the nervous and lymphoid system in the gut, plays a key role in the molecular mechanisms that orchestrate intestine organogenesis.- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_065681.1 | |
| 80.5 kDa | |
| RET Kinase Family | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Cytoplasmic, Mutant |
| Kinase Assay | |
| 1 mg | |
| aa 858 - 1114 | |
| Recombinant | |
| Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol | |
| Insect | |
| Liquid |