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  4. Invitrogen™ Human RET [S891A], GST Tag Recombinant Protein

Invitrogen™ Human RET [S891A], GST Tag Recombinant Protein

Product Code. p-7180520
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
This item is not returnable. View return policy

Product Code. 15900293

Brand: Invitrogen™ A30517

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This RET S891A recombinant human protein (658-end) was expressed in insect cells. RET S891A recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic, Mutant The gene accession number for RET [S891A] is NP_065681.1.

RET receptor tyrosine kinase or ret proto-oncogene is a member of the cadherin superfamily which are cell-surface molecules that transduce signals for cell growth and differentiation. RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. RET signaling pathway, by regulating the development of both the nervous and lymphoid system in the gut, plays a key role in the molecular mechanisms that orchestrate intestine organogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P07949
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 0.1mM PMSF, 0.1mM EDTA, 150mM NaCl, 10mM glutathione, 0.25mM DTT, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 5979
Molecular Weight (g/mol) 74.5 kDa
Name Human RET [S891A], GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias RET
Common Name RET (S891A Mutant)
Gene Symbol RET
KinaseFamily RET Kinase Family
Protein Length 658-end
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 658-end
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Form Recombinant, Active, Catalytic, Mutant
Form Liquid
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