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Refametinib, MedChemExpress

Product Code. p-200100155
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16496128 10 mg 10mg
16486516 100 mg 100mg
16472267 50 mg 50mg
16438737 5 mg 5mg
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Product Code. 16496128 Supplier Medchem Express Supplier No. HY14691

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Description

MedChemExpress Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively.

Refametinib (BAY 869766

Specifications

Chemical Name or Material Refametinib
CAS 923032-37-5
Color Earth Yellow
Purity Grade Notes Research
Molecular Formula C19H20F3IN2O5S
Quantity 10 mg
Synonym BAY 869766 RDEA119
Solubility Information DMSO : ≥ 31 mg/mL (54.16 mM)
SMILES O=S(C1(C[C@H](O)CO)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O
Molecular Weight (g/mol) 572.34
Formula Weight 572.34
Percent Purity 98.97%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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