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R&DSystems™ Recombinant Human Integrin alpha 4 beta 7/LPAM 1 Protein, CF

Product Code. 18704414
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50 μg
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Product Code. 18704414

Brand: R&DSystems™ 11509A3050

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4100.00 NOK valid until 2025-12-16
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Description

Fc Chimera

Measured by its binding ability in a functional ELISA. Recombinant Human Integrin alpha 4 beta 7/LPAM-1 Fc Chimera (Catalog # 11509-A3) binds Recombinant Human MAdCAM-1 Fc Chimera (Catalog # 6056-MC ) with an ED50 of 30.0-450 ng/mL.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P13612.3 (Integrin alpha 4) & P26010.1 (Integrin beta 7)
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 3676
Molecular Weight (g/mol) M.W.-observed: 115-135 kDa (Integrin beta 7) & 140-160 kDa (Integrin alpha 4), under reducing conditions., M.W.-theroretical: 130 kDa (Integrin alpha 4) & 104 kDa (Integrin beta 7)
Quantity 50 μg
Source Human embryonic kidney cell, HEK293-derived human Integrin alpha 4 beta 7/LPAM-1 protein Human ITGA4 (Tyr34-Gln970,R591L & R878Q) (N-terminus) Accession # P13612.3 IEGR Human IgG1 (Glu99-Lys330) (with modifications) Human ITGB7 (Glu20-His723) (N-terminus) Accession # P26010.1 IEGR Human IgG1 (Glu99-Lys330) (with modifications) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1 μg of the protein by the LAL method.
Gene Alias 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49d/beta7, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), LPAM1, LPAM-1, MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein Integrin alpha 4 beta 7/LPAM-1
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