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DiscoverX Ready-to-Assay™ MC5 Melanocortin Receptor Frozen Cells

Product Code. 17375289
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
Product Code. Quantity unitSize
17375289 2 Vials of Cells 2 ampoules
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This item is not returnable. View return policy

Product Code. 17375289

Brand: DiscoverX HTS155RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ MC5 Melanocortin Receptor Frozen Cells measure MC5R (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ MC5 Melanocortin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. α-MSH) based activation of MC5R GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress MC5R alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of MC5R , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry MC5
For Use With (Application) Frozen Cells
Primary Agonist α-MSH
Quantity 2 Vials of Cells
Target Entry MC5R
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