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  6. STEMCELL Technologies Rapamycin

STEMCELL Technologies Rapamycin

Product Code. 17130212
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Product Code. Quantity Unit Size
17130212 10 mg 10mg
15682517 1 mg 1mg
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Product Code. 17130212 Supplier STEMCELL Technologies Supplier No. 73364
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Estimated Shipment: 23-09-2026
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Descrizione

Antibiotic; mTOR pathway inhibitor; Inhibits FKBP-12

  • Rapamycin is a macrolide antibiotic and immunosuppressive compound that inhibits mammalian target of rapamycin (mTOR) signaling
  • It acts through formation of a complex with cytosolic FK-binding protein 12 (FKBP-12), which directly binds to mTOR complex 1 (mTORC1)
  • Its immunosuppressive effects are mediated through inhibition of IL-2 signaling that is critical for T-cell proliferation and activation (Gibbons et al.; Kay et al.) Rapamycin shows antifungal activity against Candida albicans and other fungi (Vézina et al.)
  • Inhibits growth of MDA-MB-468 human breast cancer cells in vitro, and inhibits tumor growth in a mouse xenograft model in vivo (Akcakanat et al.)
  • Induces autophagy in malignant glioma cells (Takeuchi et al.)

Specifica

CAS 53123-88-9
Quantity 10 mg
Percent Purity ≥95%
Titolo del prodotto
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