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  6. RAF1 Mouse anti-Human, Mouse, Clone: 1D6A1, Proteintech

RAF1 Mouse anti-Human, Mouse, Clone: 1D6A1, Proteintech

Product Code. 16808615 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16808615 20 μL 20µL
16898605 150 μL 150µL
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Product Code. 16808615

Brand: Proteintech 665921IG20UL

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Description

Mouse Monoclonal Antibody

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Specifications

Antigen RAF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1D6A1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RAF1
Gene Accession No. P04049, Q99N57
Gene Alias c Raf, CRAF, NS5, Proto oncogene c RAF, RAF, Raf 1, RAF1
Gene Symbols RAF1
Host Species Mouse
Immunogen RAF1 Fusion Protein Ag25423
Purification Method Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110157, 5894
Target Species Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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