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  7. Quinine hemisulfate monohydrate, 98+%

Quinine hemisulfate monohydrate, 98+%

Product Code. 11448896
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Product Code. 11448896

Brand: Thermo Scientific Alfa Aesar A17036.09

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Description

CAS: 6119-70-6 | C40H54N4O10S | 782.95 g/mol

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Solubility
Soluble in a mixture of chloroform and absolute alcohol (2:1).

Notes
Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 6119-70-6
Molecular Formula C40H54N4O10S
Molecular Weight (g/mol) 782.95
MDL Number MFCD00150790
InChI Key ZHNFLHYOFXQIOW-OIGVVMIYNA-N
Synonym Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate
PubChem CID 134129495
IUPAC Name (R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate
SMILES O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

Specifikationer

Melting Point 217°C to 218°C (decomposition)
Odor Odorless
Quantity 10 g
Beilstein 6113937
Sensitivity Light sensitive
Merck Index 14,8061
Solubility Information Soluble in a mixture of chloroform and absolute alcohol (2:1).
Optical Rotation −241° (c=2 in 0.1M HCl)
Formula Weight 391.47 (373.46 Anhydrous)
Percent Purity 99%
Chemical Name or Material Quinine hemisulfate monohydrate
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Säkerhet och hantering

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Produktbeteckning
  • Quinine hemisulfate monohydrate
 Signalord
  • Warning
 Riskkategorier
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Faroangivelser
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Skyddsangivelse
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
 Kompletterande information
  • MIXTURE LIST-Contains : Quinine, sulfate (2:1), dihydrate
SDS

RUO – Research Use Only

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