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Description
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Specifications
Specifications
| Antigen | QDPR |
| Applications | Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.21 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | QDPR |
| Gene Accession No. | P09417, P11348, Q8BVI4 |
| Gene Alias | DHPR, Dihydropteridine reductase, HDHPR, PKU2, QDPR, SDR33C1 |
| Gene Symbols | Qdpr |
| Show More |
Product Title
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