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PTP4A1/PRL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11508-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888633

  • 3468.15 NOK / 150µL
Estimated Shipment: 19-12-2022
to see stock.

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Description

Description

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.
Specifications

Specifications

PTP4A1/PRL1
Polyclonal
Unconjugated
PTP4A1
HH72, PRL 1, PRL1, PTP(CAAX1), PTP(CAAXI), PTP4A1, PTPCAAX1
Rabbit
Antigen Affinity Chromatography
RUO
19243, 29463, 7803
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q63739, Q78EG7, Q93096
PTP4A1
PTP4A1/PRL1 Fusion Protein Ag2067
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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