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PRSS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15005-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893964

  • 3468.15 NOK / 150µL
Estimated Shipment: 14-12-2022
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Description

Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
Specifications

Specifications

PRSS2
Polyclonal
Unconjugated
PRSS2
Anionic trypsinogen, PRSS2, Serine protease 2, TRY2, TRY8, TRYP2, Trypsin 2, Trypsin II
Rabbit
Antigen Affinity Chromatography
RUO
22072, 25052, 5645
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P00763, P07146, P07478
PRSS2
PRSS2 Fusion Protein Ag6461
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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