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Prothymosin alpha Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | Prothymosin alpha |
---|---|
Concentration | 0.4 mg/mL |
Applications | Immunohistochemistry (Paraffin) |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16806893
|
Proteintech
10480-1-AP-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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16896883
|
Proteintech
10480-1-AP-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 08-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Prothymosinalpha(PTalpha) is a nuclear protein that is widely expressed in mammalian tissues, including kidney, liver, spleen, normal lymphocytes, human T cell leukemia virus-infected T cells and myeloma cells. The human PTalpha gene maps to chromosome 2 and encodes a protein that exhibits punctuated nuclear distribution,which correlates to transcription sites. PTalpha is a chromatin-remodeling protein that was initially thought to mediate T lymphocyte maturation,but subsequently has been shown to be involved in cellcycle progression,proliferation and cell differentiation. PTalpha is thought to be transported into the nucleus by the karyopherin beta1-Rch-1 complex, where it associates with Histones H2A, H2B, H3 and H4. Also, PTalpha is phosphorylated on Thr 7 and Thr 12 or 13 by Prothymosin alpha-phosphorylating kinase (PTalphaK) in amitogen activating pathway. The amino terminus of PTalpha iscleaved to produce a secreted, biologically active peptide thymosin alpha1,whichmay be used as an immunomodulatorin cancer patients and patients with chronic active hepatitis,or as an immunoen hancer of vaccinesin immunocompromised individuals.Specifications
Prothymosin alpha | |
Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
Human | |
P06454 | |
5757 | |
Prothymosin alpha Fusion Protein Ag0732 | |
Primary | |
-20°C | |
PTMA |
0.4 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Prothymosin alpha, prothymosin, alpha, PTMA, TMSA | |
PTMA | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |