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Progesterone, 98%, Thermo Scientific Chemicals

Product Code. p-3737256 Shop All Thermo Scientific Chemicals Products
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Quantity:
5 g
25 g
100 g
Packaging:
Glass bottle
Unit Size:
100g
25g
5g
Product Code. Quantity Packaging unitSize
10368310 5 g Glass bottle 5g
10328360 25 g Glass bottle 25g
10277303 100 g Glass bottle 100g
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Product Code. 10368310

Brand: Thermo Scientific Acros 225650050

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Descripción

Progesterone, CAS # 57-83-0, is a naturally occurring hormone required for maintenance of the uterine endothelium and suppression of estrogens.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Progesterone is a sex hormone required for suppression of estrogen signaling and is also involved in transcriptional activation

• Progesterone maintains the uterine endothelium and sustains pregnancy through suppression of muscle contractility

Applications

• Progesterone signaling is relevant to the study of breast cancer

Literature References

Kim, O.; Park, E.Y.; Kwon, S.Y.; Shin, S.; Emerson, R.E.; Shin, Y.H.; DeMayo, F.J.; Lydon, J.P.; Coffey, D.M.; Hawkins, S.M.; Quilliam, L.A.; Cheon, D.J.; Fernández, F.M.; Nephew, K.P.; Karpf, A.R.; Widschwendter, M.; Sood, A.K.; Bast, R.C. Jr.; Godwin, A.K.; Miller, K.D.; Cho, C.H.; Kim, J. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020, 117(50), 31993-32004.

Jain, V.; McDonald, S.D.; Mundle, W.R.; Farine, D. Guideline No. 398: Progesterone for Prevention of Spontaneous Preterm Birth. J Obstet Gynaecol Can. 2020, 42(6), 806-812.

TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 57-83-0
Molecular Formula C21H30O2
Molecular Weight (g/mol) 314.46
MDL Number MFCD00003658
InChI Key RJKFOVLPORLFTN-LEKSSAKUSA-N
Synonym progesterone, agolutin, luteohormone, pregn-4-ene-3,20-dione, crinone, 4-pregnene-3,20-dione, corpus luteum hormone, progestin, syngesterone, utrogestan
PubChem CID 5994
ChEBI CHEBI:17026
IUPAC Name (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

Especificaciones

Melting Point 126°C to 131°C
Color Brown-Yellow to Yellow
Loss on Drying 0.5% max. (500 mg, 105°C, 2 hrs)
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Packaging Glass bottle
Quantity 5 g
Merck Index 15, 7889
Specific Rotation Condition +190° (20°C c=1,ethanol)
Specific Rotation + 190
Solubility Information Solubility in water: insoluble. Other solubilities: soluble in alcohol,acetone,dioxane,conc. h2so4
Formula Weight 314.46
Percent Purity 98%
Physical Form Crystalline Powder, Crystals or Chunks
Chemical Name or Material Progesterone
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Seguridad y manipulación

compliance-icons
Nombre del producto
  • Progesterone
 Palabra de advertencia
  • Warning
 Clasificación
  • Carcinogenicity Category 2
 Indicaciones de peligro
  • H351-Suspected of causing cancer.
 Consejos de prudencia
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
SDS

RUO – Research Use Only

Título del producto
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