missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 10008252

Invitrogen™ PRAS40 Monoclonal Antibody (73P21)
GREENER_CHOICE

Product Code. 10008252
Change view
Click to view available options
Quantity:
100 μg
Unit Size:
Each
Product Code. Quantity unitSize
10008252 100 μg Each
1 options
This item is not returnable. View return policy

Product Code. 10008252

Brand: Invitrogen™ AHO1031

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

PRAS40 Monoclonal Antibody for Western Blot, IHC (P), ICC/IF, IP

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRAS40
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 73P21
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide
Gene AKT1S1
Gene Accession No. Q96B36
Gene Alias 1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1
Gene Symbols AKT1S1
Host Species Mouse
Immunogen Recombinant full length human PRAS40 expressed in E. coli.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84335
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.