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Gibco™ Porcine IL-4, AOF Recombinant Protein

Product Code. 17646595
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Quantity:
1 mg
100 μg
500 μg
Unit Size:
100µg
1mg
500µg
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Product Code. 17646595

Brand: Gibco™ RP87793

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This item is not returnable. View return policy

Description

Recombinant Protein

Animal Origin Free Reconstitution: Sterile Water at 0.1 mg/mL

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q04745
For Use With (Application) Control
Formulation 10 mM sodium phosphate with no preservative; pH 7.5
Gene ID (Entrez) 397225
Molecular Weight (g/mol) 12.7 kDa
Name Porcine IL-4, AOF
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration ≤0.1 EU/μg
Gene Alias B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4 delta2; interleukin 4 variant IL-4 delta3; interleukin 4 variant IL-4 int2A; interleukin 4 variant IL-4 int3A; interleukin 4 variant IL-4 int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Common Name IL-4
Gene Symbol Il4
Biological Activity ED50 = 2 ng/mL; determined by the dose-dependent proliferation of TF-1 cells.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥95% by SDS-Page
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