missing translation for 'onlineSavingsMsg'
Learn More
Learn More
PKC iota Mouse anti-Human, Mouse, Rat, Clone: 3A1B6, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66493-1-IG-150UL
This item is not returnable.
View return policy
Description
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.Specifications
| PKC iota | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| F1M7Y5, P41743, Q62074 | |
| Prkci | |
| PKC iota Fusion Protein Ag4990 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2a |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 3A1B6 | |
| Unconjugated | |
| PRKCI | |
| aPKC lambda/iota, DXS1179E, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota | |
| Mouse | |
| Protein A | |
| RUO | |
| 18759, 5584, 84006 | |
| -20°C | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction