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Invitrogen™ Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), PE, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
2160.00 NOK - 5440.00 NOK
Specifications
| Antigen | Phospho-Ask1 (Ser83) |
|---|---|
| Clone | Ask1S83-G4 |
| Applications | Flow Cytometry |
| Classification | Recombinant Monoclonal |
| Conjugate | PE |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17176848
|
Invitrogen™
MA537261 |
10 Tests |
2160.00 NOK
Pack of 10 |
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|
17106568
|
Invitrogen™
MA536974 |
100 Tests |
5440.00 NOK
Pack of 100 |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
MAP3K5 (ASK1) is a serine/threonine kinase that is abundantly expressed in human heart and pancreas and are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is expressed in variety of human and mouse tissues.Specifications
| Phospho-Ask1 (Ser83) | |
| Flow Cytometry | |
| PE | |
| Rabbit | |
| Human, Mouse, Rat | |
| O35099, Q99683 | |
| 26408, 365057, 4217 | |
| A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1. | |
| Primary | |
| 4°C | |
| MAP3K5 |
| Ask1S83-G4 | |
| Recombinant Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 0.20% BSA and 0.09% sodium azide | |
| 7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4 | |
| MAP3K5 | |
| IgG κ | |
| Protein A/G | |
| Antibody |
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