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  6. PELI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

PELI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16889533 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16889533 150 μL 150µL
16899533 20 μL 20µL
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Product Code. 16889533

Brand: Proteintech 120531AP150UL

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Description

Rabbit Polyclonal Antibody

This antibody may cross react with Pellino-3.

The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-Kappa-B. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon; and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.

Specifications

Antigen PELI1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene PELI1
Gene Accession No. Q8C669, Q96FA3
Gene Alias PELI1, Pellino 1, pellino homolog 1 (Drosophila), PRISM, Protein pellino homolog 1
Gene Symbols PELI1
Host Species Rabbit
Immunogen PELI1 Fusion Protein Ag2683
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305549, 57162, 67245
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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