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Description
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
Specifications
Specifications
| Antigen | PDH E1 alpha |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | PDHA1 |
| Gene Accession No. | P08559, P26284, P35486 |
| Gene Alias | PDH E1 alpha, PDH E1alpha, PDHA1, PDHE1 A type I, pyruvate dehydrogenase E1 alpha subunit |
| Gene Symbols | Pdha1 |
| Show More |
Product Title
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