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PD-L1/CD274 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2B11D11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66248-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887945

  • 1281.92 NOK / 20µL
Estimated Shipment: 13-12-2022
to see stock.

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Description

Description

PD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.
Specifications

Specifications

PD-L1/CD274
Monoclonal
1.55 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9EP73, Q9NZQ7
CD274
PD-L1/CD274 Fusion Protein Ag12443
20 μL
Primary
Rat, Mouse, Porcine, Human
Antibody
IgG1
Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
2B11D11
Unconjugated
CD274
B7 H, B7 H1, B7 homolog 1, B7H1, CD274, CD274 molecule, PD L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, PD-L1/CD274, Programmed death ligand 1
Mouse
Protein G
RUO
29126, 499342, 574058, 60533
-20°C
Liquid
Videos
SDS
Documents
Certificates
Special Offers

Special Offers