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DiscoverX PathHunter™ eXpress EGFR/EGFR Dimerization Assay
Description
The PathHunter™ EGFR/EGFR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. EGF) induced dimerization of EGFR/EGFR receptors. This product uses EFC technology. The cell line included overexpresses EGFR target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/EGFR , detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Specifications
Specifications
| Assay Entry | EGFR/EGFR Dimerization |
| For Use With (Application) | Assay-Ready eXpress Kits |
| Primary Agonist | Recombinant Human EGF |
| Quantity | 1,000 dp (10 x 96-well) |
| Target Entry | EGFR/EGFR |
| Cell Line | U2OS |
| Target | EGFR/EGFR |
Product Title
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