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DiscoverX PathHunter™ eXpress EGFR/EGFR Dimerization Assay

Product Code. 17314169
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
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17314169 1,000 dp (10 x 96-well) 1 set
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Product Code. 17314169 Supplier DiscoverX Supplier No. 930989E3CP5L

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Description

The PathHunter™ eXpress EGFR/EGFR Dimerization Assay measures ligand-induced dimerization of EGFR/EGFR . eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ EGFR/EGFR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. EGF) induced dimerization of EGFR/EGFR receptors. This product uses EFC technology. The cell line included overexpresses EGFR target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/EGFR , detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry EGFR/EGFR Dimerization
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist Recombinant Human EGF
Quantity 1,000 dp (10 x 96-well)
Target Entry EGFR/EGFR
Cell Line U2OS
Target EGFR/EGFR
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