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DiscoverX PathHunter™ eXpress BMPR1A/ACVR2 Dimerization Assay

Product Code. 17354279
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
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17354279 200 dp (2 x 96-well) 1 set
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Product Code. 17354279 Supplier DiscoverX Supplier No. 931037E3CP5M

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Description

The PathHunter™ eXpress BMPR1A/ACVR2 Dimerization Assay measures ligand-induced dimerization of BMPR1A/ACVR2 . eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ BMPR1A/ACVR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. BMP-4) induced dimerization of BMPR1A/ACVR2 receptors. This product uses EFC technology. The cell line included overexpresses BMPR1A target protein fused to PK alongside ACVR2 target protein fused to EA. Upon ligand-induced dimerization of BMPR1A/ACVR2 , detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry BMPR1A/ACVR2 Dimerization
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist BMP-4
Quantity 200 dp (2 x 96-well)
Target Entry BMPR1A/ACVR2
Cell Line U2OS
Target BMPR1A/ACVR2
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