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PANX1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12595-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16890384

  • 1281.92 NOK / 20µL
Estimated Shipment: 15-12-2022
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Description

Description

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Specifications

Specifications

PANX1
Polyclonal
Unconjugated
PANX1
MRS1, pannexin 1, PANX1, PX1, UNQ2529
Rabbit
Antigen Affinity Chromatography
RUO
24145
-20°C
Liquid
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
0.14 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q96RD7
PANX1
PANX1 Fusion Protein Ag3174
20 μL
Primary
Human
Antibody
IgG
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