missing translation for 'onlineSavingsMsg'
Learn More

PANK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11001-1-AP-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16887763

  • 1281.92 NOK / 20µL
Estimated Shipment: 19-12-2022
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).
Specifications

Specifications

PANK2
Polyclonal
Unconjugated
PANK2
C20orf48, HARP, hPanK2, HSS, NBIA1, PANK2, pantothenate kinase 2, Pantothenic acid kinase 2, PKAN
Rabbit
Antigen Affinity Chromatography
RUO
296167, 74450, 80025
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9BZ23
Pank2
PANK2 Fusion Protein Ag1413
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers