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P glycoprotein Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22336-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891865

  • 1281.92 NOK / 20µL
Estimated Shipment: 19-12-2022
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Description

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Specifications

Specifications

P glycoprotein
Polyclonal
Unconjugated
ABCB1
ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1
Rabbit
Antigen Affinity Chromatography
RUO
18669, 18671, 5243
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
0.48 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P06795, P08183, P21447
ABCB1, Abcb1a, Abcb1b
P glycoprotein Fusion Protein Ag17811
20 μL
Primary
Human, Mouse
Antibody
IgG
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