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Proteintech OPTN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10837-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
10837-1-AP recognizes 66 and 70-74 kDa band. The additional 70-74 kDa band is due to phosphorylation.
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.Specifications
| OPTN | |
| Polyclonal | |
| Unconjugated | |
| OPTN | |
| E3 14.7K interacting protein, FIP 2, FIP2, GLC1E, HIP 7, HIP7, Huntingtin yeast partner L, HYPL, NEMO related protein, NRP, optineurin, OPTN, TFIIIA INTP | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10133, 246294, 71648 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry, Flow Cytometry, Immunoprecipitation | |
| 0.35 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8K3K8, Q8R5M4, Q96CV9 | |
| Optn | |
| OPTN Fusion Protein Ag1272 | |
| 20 μL | |
| Primary | |
| Rat, Mouse, Human | |
| Antibody | |
| IgG |