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NR3C2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7209458 Shop All Proteintech Products
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150 μL
20 μL
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150µL
20µL
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16871405 20 μL 20µL
16861405 150 μL 150µL
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Product Code. 16871405 Supplier Proteintech Supplier No. 218541AP20UL

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Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody, specifically reacts with the 107 kDa MCR protein.

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor (MR) and that complex′s subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain MR. The corresponding gene for the mineralocorticoid receptor is NR3C2.

Specifications

Antigen NR3C2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NR3C2
Gene Accession No. P08235, P22199, Q8VII8
Gene Alias MCR, Mineralocorticoid receptor, MLR, MR, NR3C2
Gene Symbols NR3C2
Host Species Rabbit
Immunogen NR3C2 Fusion Protein Ag16410
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110784, 25672, 4306
Target Species Rat, Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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