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  6. NOTCH3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

NOTCH3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16896565 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16896565 20 μL 20µL
16886565 150 μL 150µL
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Product Code. 16896565

Brand: Proteintech 551141AP20UL

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Description

Rabbit Polyclonal Antibody

The antibody is specific to NOTCH3.

NOTCH3 is the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal domit arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Specifications

Antigen NOTCH3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NOTCH3
Gene Accession No. Q61982, Q9UM47
Gene Alias CADASIL, CASIL, Notch 3, Notch homolog 3 (Drosophila), NOTCH3
Gene Symbols Notch3
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18131, 4854
Target Species Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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