missing translation for 'onlineSavingsMsg'
Learn More
Learn More
NOTCH3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 55114-1-AP-150UL
This item is not returnable.
View return policy
Description
The antibody is specific to NOTCH3.
NOTCH3 is the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal domit arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).Specifications
| NOTCH3 | |
| Polyclonal | |
| Unconjugated | |
| NOTCH3 | |
| CADASIL, CASIL, Notch 3, Notch homolog 3 (Drosophila), NOTCH3 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 18131, 4854 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.19 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q61982, Q9UM47 | |
| Notch3 | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction