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NGEF Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13271-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.Specifications
| NGEF | |
| Polyclonal | |
| Unconjugated | |
| NGEF | |
| EPHEXIN, Ephexin 1, NGEF | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 25791, 53972 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8CHT1, Q8N5V2 | |
| NGEF | |
| NGEF Fusion Protein Ag3967 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |