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NGEF Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13271-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891394

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
to see stock.

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Description

Description

Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.
Specifications

Specifications

NGEF
Polyclonal
Unconjugated
NGEF
EPHEXIN, Ephexin 1, NGEF
Rabbit
Antigen Affinity Chromatography
RUO
25791, 53972
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8CHT1, Q8N5V2
NGEF
NGEF Fusion Protein Ag3967
150 μL
Primary
Mouse, Human
Antibody
IgG
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Special Offers

Special Offers