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  6. Neomycin Sulfate, MP Biomedicals™

Neomycin Sulfate, MP Biomedicals™
BIOPHARMA

Product Code. 17670887 Shop All MP Biomedicals Products
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Product Code. Quantity unitSize
17670887 100 g 100g
17650887 5 g 5g
17660887 25 g 25g
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Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Product Code. 17670887

Brand: MP Biomedicals 0218061080

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This item is not returnable. View return policy
Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Description

Acts against both gram-positive and gram-negative bacteria. Neomycin Sulfate, MP Biomedicals is produced by Streptomyces containing a minimum of 85% neomycin B.

This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.

Applications:

  • As a selection agent for prokaryotic cells transformed using the neo selectable marker gene
  • To study ototoxic side effects of antibiotics and platelet-derived growth factor responses in certain fibroblasts
  • In the extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins
  • It is recommended for use in cell culture applications at 50mg/L
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1405-10-3
Molecular Formula C23H48N6O17S
Molecular Weight (g/mol) 712.72
MDL Number MFCD29905465
InChI Key OIXVKQDWLFHVGR-DJUBFIBWNA-N
PubChem CID 124080932
SMILES OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O

Specifications

Physical Form Powder
pH 5 to 7.5
Loss on Drying <8.0%
Quantity 100 g
Solubility Information H2O soluble (50mg/mL)
IUPAC Name (2S,3R,4S,5S,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3R,4S,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
Formula Weight 908.9g/mol
Grade USP

Safety and Handling

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Product Identifier
  • Neomycin Sulphate, USP
 Signal Word
  • Danger
 Hazard Category
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P321-Specific treatment (see on this label).
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Neomycin Sulphate
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