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Nalidixic acid sodium salt

Artikelnummer. 15445749
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Artikelnummer. 15445749 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J63550.06
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Beschreibung

Nalixidic acid, CAS # 389-08-2, is a quinolone antibiotic that inhibits cell division. | CAS: 3374-05-8 | C12H11N2NaO3 | 254.22 g/mol

Nalidixic acid sodium salt is an antibacterial agent, which is inhibitor of bacterial DNA polymerase & avian myeloblastoma virus reverse transcriptase. The compound inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Nalidixic acid is a monocarboxylic acid and quinoline antibiotic
• Nalixidic acid is a DNA synthesis inhibitor that acts by preventing DNA gyrase activity

Application

• Nalidixic acid is most effective against gram-negative bacteria, including Enterobacter species and other common resistant species
• It is suitable in laboratory applications for research of the mechanisms of gyrase activity and metabolic pathways related to DNA synthesis

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 5-8-3374
Molecular Formula C12H11N2NaO3
Molecular Weight (g/mol) 254.22
MDL Number MFCD00064376
InChI Key ROKRAUFZFDQWLE-UHFFFAOYSA-M
Synonym nalidixic acid sodium salt, baktogram, nalidixic acid sodium, sodium nalidixate, chemiurin, dixilina, nalidixate sodium anhydrous, nalidixate sodium, nalidixate sodium anhydrous usan, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
PubChem CID 3864541
IUPAC Name sodium;1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate
SMILES CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)[O-].[Na+]

Spezifikation

Melting Point >280°C
Color White to Yellow
Quantity 5 g
Beilstein 3580062
Solubility Information Soluble at 50mg/ml in water
Formula Weight 254.22
Physical Form Powder
Chemical Name or Material Nalidixic acid sodium salt

Sicherheit und Handhabung

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Produktidentifikator
  • Nalidixic acid sodium salt
 Signalwort
  • Danger
 Gefahrenkategorie
  • Acute toxicity Category 4
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Gefahrenhinweis
  • H302-Harmful if swallowed.
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
 Sicherheitshinweis
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-[In case of inadequate ventilation] wear respiratory protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
 Ergänzende Informationen
  • MIXTURE LIST-Contain: Nalidixic acid sodium salt
Sicherheitsdatenblatt (SDS)

RUO – Research Use Only

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