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Nalidixic acid, 99.5%

Product Code. 10373622 Shop All Thermo Scientific Chemicals Products
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Product Code. 10373622 Supplier Thermo Scientific Acros Supplier No. 169900050
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Description

Nalixidic acid, or nalixidin, CAS # 389-08-2, is a quinolone antibiotic used to inhibit DNA gyrase and prevent cell division. | CAS: 389-08-2 | C12H12N2O3 | 232.24 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Nalixidic acid is a synthetic quinolone that is a monocarboxylic acid composed of 1,8-naphthyridine substituted with carboxylic acid, ethyl, and methyl groups

• Nalixidic acid is a DNA gyrase inhibitor that prevents DNA synthesis and subsequent cell divisions

Applications

• Nalixidic acid is primarily effective against gram-negative bacteria

• It may be useful for bacterial resistance studies and laboratory research on drug allergies and cross-reactivity

• Nalixidic acid is suitable for high-performance liquid chromatography (HPLC) and related biochemistry laboratory applications

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 389-08-2
Molecular Formula C12H12N2O3
Molecular Weight (g/mol) 232.24
MDL Number MFCD00006884
InChI Key MHWLWQUZZRMNGJ-UHFFFAOYSA-N
Synonym nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
PubChem CID 4421
ChEBI CHEBI:100147
IUPAC Name 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
SMILES CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O

Specifications

CAS Min % 99.4
CAS Max % 100.0
Melting Point 225.0°C to 231.0°C
Color White to Yellow
Infrared Spectrum Authentic
Assay Percent Range 99.5%
Packaging Glass bottle
Quantity 5 g
Beilstein 25, V,7, 384
Merck Index 15, 6444
Solubility Information Solubility in water: 0.1g/L (23°C). Other solubilities: soluble in alkali solutions,35mg/mL chloroform- 1.6mg/mL toluene (23°C),1.3mg/mL methanol- 0.9mg/mL ethanol (23°C),0.1mg/mL ether (23°C)
Formula Weight 232.24
Percent Purity 99.5%
Physical Form Powder
Chemical Name or Material Nalidixic acid, 99.5%
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Safety and Handling

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Product Identifier
  • Nalidixic acid
 Signal Word
  • Danger
 Hazard Category
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

RUO – Research Use Only

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